Stannanes, also known as organotins, are extremely versatile synthons that can be utilized in palladium-catalyzed cross coupling reactions (Stille Reaction1). These cross coupling reactions, which form C-C bonds, are widely used in natural product synthesis and in drug discovery for the preparation of small molecules2-4. Synthonix offers and stocks a wide variety of stannane synthons. We also supply SnAP reagents5, which can be used for the preparation of morpholines, piperazines, and other related ring systems. If you don't see what you are looking for please contact us. We offer custom synthesis to provide our customers with all their synthetic needs.

1Stille, J. K. Angew. Chem. Int. Ed. Engl. 1986, 25, 508-524.
2Wollenberg, R. H.; Albizati, K. F.; Peries, R. J. Am. Chem. Soc. 1977, 99, 7365-7. (E2342)
3Kosugi, M.; Sumiya, T.; Obara, Y.; Suzuki, M.; Sano, H.; Migita, T. Bull. Chem. Soc. (Japan), 1987,60, 767-8. (T5149)
4Heldmann, D. K.; Sauer, J. Tett. Lett. 1997, 38, 5791-4. (T2247)
5Luescher, M. U.; Vo, C. T.; Bode, J. W. Org. Let. 2014, 16, 1236-9.

catalytic cycle stille reaction
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