2-Oxa-6-azaspiro[3.3]heptane hemioxalate
Oxetane ring is a good isosteric replacement for methylene and gem dimethyl motif for improving key physicochemical parameters to assist property guided drug discovery.Introduction of Oxetane motif at different locations has been shown to:
- Improve the physico- and biochemical properties for the active scaffold
- Enhance solubility, reduce lipophilicity, amphiphilicity, and hERG liability
- Impart robust chemical stability under various acidic and basic conditions
- Improve resistance towards metabolic degradation
- SKU: O5816
- Name: 2-Oxa-6-azaspiro[3.3]heptane hemioxalate
- CAS: 1045709-32-7
- MDL: MFCD11976178
- Formula: C5H9NO.1/2(C2H2O4)
- MW: 144.15
- Purity: 97%
- InChi Key: HPJALMWOZYIZGE-UHFFFAOYSA-N
MSDS: Download MSDS
Additional Info
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